This Gong Open provides Right, and there are the epitopes on what CD22 special Iso Kang Body. The anti-Body can control Treatment, ?Broken with the more Seed of what and Prison Measuring Should is used, and also a And is provided. The anti-CD22 Kang Body of this Gong Open can in some cases Shang its Fine cellular surface of what Biao Da CD22 Fine Bao Zhong Lure Guide apoptosis. Zhu Questions Kang Body spy Iso Knot closes CD22 polypeptide, and wherein epitope includes the amino acid Disabled base (for example, in amino acid 1-847 of CD22 amino acid sequence, amino acid 1-759 ,-670 Inner of amino acid 1-751 or amino acid 1) of CD22 antigen Inner.本公開提供對存在於CD22上的表位有特異性的抗體。所述抗體可用於多種治療、診斷和監測應用,其也一併提供。本公開的抗‑CD22抗體可在一些情况下在於其細胞表面上表達CD22的細胞中誘導凋亡。主題抗體特異性結合CD22多肽,其中表位包含CD22抗原內的氨基酸殘基(例如,在CD22氨基酸序列的氨基酸1‑847,氨基酸1‑759,氨基酸1‑751,或氨基酸1‑670內)。