Kiyoyuki Omoto,Robert McKenzie Owen,David Cameron Pryde,Christine Ann Louise Watson,Mifune Takeuchi
申请号:
US14725234
公开号:
US20150259352A1
申请日:
2015.05.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.