SARMIENTO, ROSA MARIA RODRIGUEZ,沙米恩托 罗沙 玛莉亚 罗瑞格,沙米恩托 羅沙 瑪莉亞 羅瑞格,WICHMANN, JUERGEN,威奇曼 吉尔金,威奇曼 吉爾金
申请号：
TW101104803
公开号：
TW201309667A
申请日:
2012.02.14
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein n, Y, R1, R2, R3, and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.本發明係關於式(I)之5-HT2A及D3受體之新穎雙重調節劑其中n、Y、R1、R2、R3及R4係如本文中所述;以及其醫藥上可接受之鹽及酯。本發明進一步係關於式(I)化合物之製造、包含其之醫藥組合物及其作為藥劑之用途。
