A fluidic cartridge for use with a dialysis system, a method of manufacturing the fluidic cartridge, a dialysis machine and a method of operating the dialysismachine with the fluidic cartridge. The fluidic cartridge has a data storage unit, the data storage unit stores data relating to one or more physical properties of the cartridge. A cartridge for use in a portable dialysis machine and a portable dialysis machine. The cartridge has a data storage unit, the data storage unit stores data relating to sterilisation of the cartridge.