Disclosed are compounds of Formula (IA), salts thereof, and methods for their preparation. Also disclosed are compounds of Formula (I), which differ from Formula (IA) in that the bicyclic moiety AC-AB of (IA) is instead a pyrazole ring. Specific examples of compounds of Formula (IA) and Formula (I) include: 3-[({ 4-[(Cyclohexyl{ 3-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-4-yl} methyl)amino]phenyl} carbonyl)amino]propanoic acid, 3-[{ [4-({ Cyclohexyl[1-(3-methoxyphenyl)-3-methyl-1H-pyrazol-4-yl]methyl} amino)phenyl]carbonyl} (methyl)amino]propanoic acid, and 3-{ [(5-{ [Cyclohexyl(5-fluoro-3-methyl-1-benzofuran-2-yl)methyl]amino} pyridin-2-yl)carbonyl](methyl)amino} propanoic acid. The compounds are useful as glucagon antagonists and can operate as sugar production-suppressive agents for treating diabetes.
