A system may include a stone analyzer, a controller, a laser generator, and a beam combiner. The stone analyzer may be configured to generate an output relating to a natural or resonance frequency of a kidney or bladder stone. The controller may be configured to determine the natural or resonance frequency of the stone based on the output from the stone analyzer, and match a resultant pulse repetition rate with the natural or resonance frequency. The laser generator may be configured to generate at least two laser pulse trains, with each laser pulse train including laser pulses at a pulse repetition rate. The beam combiner may be configured to combine the at least two laser pulse trains into a combined laser pulse train including laser pulses at the resultant pulse repetition rate.