ANTITUMOR COMPOUND TARGETING IDH2 MUTATION AND METHOD OF USE THEREOF

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专利权人:

CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.;LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.;CENTAURUS BIOPHARMA CO., LTD.

发明人:

Shulong WANG,Na ZHAO,Xijie LIU,Yuandong HU,Hui ZHANG,Hong LUO,Yong PENG,Dengming XIAO,Yongxin HAN,Xiquan ZHANG,Xin TIAN

申请号：

US15748488

公开号：

US20180222853A1

申请日:

2016.07.29

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present application relates to compounds represented by general formula (I), general formula (II) or general formula (III), and pharmaceutically acceptable salts or hydrates thereof, preparation methods thereof, and pharmaceutical compositions thereof. The compounds represented by general formula (I), general formula (II) or general formula (III) have inhibitory activities against isocitrate dehydrogenase 2 (IDH2), thereby being capable of treating IDH2 mutation-induced cancers.

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中国工程科技知识中心

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