Novel siRNA and method of using the same

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专利权人:

クアーク・ファーマスーティカルス、インコーポレイテッド

发明人:

フェインステイン、エレナ,メット、イゴア,スカリター、ラミ,カリンスキ、ハガー,イデルソン、グレゴリー・ヒルシュ

申请号：

JP2014203377

公开号：

JP5925856B2

申请日:

2014.10.01

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The invention relates to compounds, in particular siRNAs, which inhibit the expression of specific human genes. The invention also relates to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The present invention also provides a method of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions comprising administering to a subject in need of treatment for such disease or condition and/or symptom the compound or the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject. The invention also provides antibodies which inhibit specified human polypeptides and pharmaceutical compositions comprising one or more such antibodies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/