SHINO HANABUCHI,JOHN MUMM,DANIEL J. FREEMAN,JINLIN JIANG,SOMEET NARANG,RONALD HERBST,DANIELLE TOWNSLEY,GIANLUCA CARLESSO,TAEIL KIM
申请号:
US16718920
公开号:
US20200199567A1
申请日:
2019.12.18
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure provides methods for the selection and isolation of T cells expressing programmed cell death 1 (PD-1) and for selecting a PD-1 expression level of the isolated PD-1 expressing T cells. The disclosure also provides methods of large scale expansion of selected and isolated PD-1 expressing T cells, as well as methods for treating a subject comprising administering selected and isolated PD-1 expressing T cells to the subject.