METHODES DE REDUCTION DE LA PROTEINURIE CHEZ UN SUJET HUMAIN SOUFFRANT D'UNE NEPHROPATHIE AUX IMMUNOGLOBULINES A

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专利权人:

UNIVERSITY OF LEICESTER;OMEROS CORPORATION

发明人:

BRUNSKILL, NIGEL JOHN,DEMOPULOS, GREGORY A.,DUDLER, TOM,SCHWAEBLE, HANS-WILHELM

申请号：

CA3039927

公开号：

CA3039927A1

申请日:

2017.10.12

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

In one aspect, the invention provides methods for reducing proteinuria in a human subject suffering, or at risk of developing Immunoglobulin A Nephropathy (IgAN). The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory antibody effective to inhibit MASP-2-dependent complement activation.

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