NIROGI, RAMAKRISHNA,SHINDE, ANIL KARBHARI,MOHAMMED, ABDUL RASHEED,JAYARAJAN, PRADEEP,BHYRAPUNENI, GOPINADH,JASTI, VENKATESWARLU
申请号：
CA3033050
公开号：
CA3033050A1
申请日:
2017.08.14
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to a combination of histamine-3 receptor inverse agonist, acetylcholinesterase inhibitor and NMDA receptor antagonist. Also, the present invention provides histamine-3 receptor (H3R) inverse agonist, or the 10 pharmaceutically acceptable salt(s) thereof in combination with or as adjunct to acetylcholinesterase inhibitor and N-Methyl-D-aspartate (NMDA) receptor antagonist and their use in the treatment of cognitive disorders. The present invention further provides the pharmaceutical composition containing the said combination.
