VON GUNTEN STEPHAN,WEHRLI MARC,ZUERCHER ADRIAN,MIESCHER SYLVIA
申请号:
IN5428/CHENP/2013
公开号:
IN2013CN05428A
申请日:
2013.07.09
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The invention relates to the use of CD89 activating molecules in particular Fc alpha comprising molecules and more particularly IgA for inducing apoptosis in neutrophils. Anti CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils such as autoimmune disorders inflammatory disorders NETosis or cystic fibrosis.