KAUFMANN, HITTO,BECKER, ERIC,FLORIN, LORE,FUSSENEGGER, MARTIN,PENG, REN-WANG,STUDTS, JOEY, M
申请号:
NZ58603708
公开号:
NZ586037A
申请日:
2008.12.19
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is an in vitro method of producing a heterologous protein of interest in a hamster or human cell comprising a) Increasing the expression of at least one gene encoding a protein from the SEC1/Munc18 group of proteins (SM proteins) and b) Effecting the expression of said heterologous protein of interest, whereby the protein of interest is a membrane or secreted protein, and whereby at least one gene in step a) encodes Munc18c.