The invention relates to an injection device with a luer fitting (250). The injection device has a compressible syringe body defining a reservoir. A male luer fitting (250) has a channe. A first connecting structure is arranged on said male luer fitting between said base end and said luer tip. A shield cap (260) is arranged on the male luer fitting (250) and has a second connecting structure interacting with said first connecting structure to prevent inadvertent movement of said shield cap relative to said male luer fitting when said shield cap is arranged at said first position. A first seal (270) is provided for sealing said channel at said luer tip and preventing leakage therethrough of content from said reservoir at least when the shield cap is at said first position. A second seal (280) is arranged between said shield cap and said male luer fitting for sealing the outer surface and the luer tip of said male luer fitting from outside contamination. The second seal (280) is formed by said first and second connecting structures when the shield cap is arranged at the first position. The shield cap is movable relative to said male luer fitting to a second position from said first position to break the first seal.La présente invention concerne un dispositif d'injection (110), équipé d'un raccord Luer. Ledit dispositif d'injection comporte un corps de seringue compressible (137) délimitant un réservoir (146). Un conduit (152) permettant d'acheminer le contenu du réservoir traverse le raccord Luer mâle (150) qui comporte également un embout Luer au niveau de son extrémité opposée à son extrémité inférieure. Une première structure de liaison (182) est disposée sur ledit raccord Luer mâle entre ladite extrémité inférieure et ledit embout Luer. Un capuchon protecteur (160) est disposé sur le raccord Luer mâle. Le capuchon protecteur comporte une seconde structure de liaison interagissant avec ladite première structure de liaison pour éviter tout mouvement involontaire dud