Being the organism fusion material which includes the carrier material where the particle of the spherical surface is connected share, the aforementioned spherical particle is formed by the polymer chain which contains approximately 30 - 10000 monomer units which are induced from the single cyclic polycyclic type alkene polymerization, through the hydrolysis type bridge, is substituted in the aforementioned polymer unit it is shared is connected by the R chain which includes the ethylene poly- oxide which by when, is substituted and by the reactivity functional group which participates in the connection with the active ingredient, the aforementioned R chain regards the aforementioned organism fusion material which it is shared is connected to the aforementioned monomer unit. In addition as for use of the organism fusion material of this invention concerning production of the medicine composition and the cosmetics composition or surface coating it is disclosed.球面の粒子が共有的に結合される担体材料を含む生体融合材料であって、前記球状粒子は、単環式多環式アルケン重合から誘導される約30~10000モノマーユニットを含有するポリマー鎖によって形成され、加水分解型ブリッジを介して前記ポリマーユニットに場合により共有結合されるエチレンポリオキシドを含むR鎖によって置換され、及び有効成分との連結に関与する反応性官能基によって置換され、前記R鎖は、前記モノマーユニットに共有結合される前記生体融合材料に関する。医薬組成物及び化粧品組成物の製造又は表面コーティングについての本発明の生体融合材料の使用はまた開示される。