AN IMPROVED PROCESS FOR BENDAMUSTINE HYDROCHLORIDE

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专利权人:

发明人:

GURJAR MUKUND KESHAV,CHAVAN ANIL BHAUSAHEB,MAIKAP GOLAKCHANDRA SUDHARSHAN,DESHMUKH SANJAY SHANKAR,MEHTA SAMIT SATISH

申请号：

IN1237/MUM/2012

公开号：

IN2012MU01237A

申请日:

2012.04.16

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

A process for preparation of bendamustine hydrochloride comprising, chlorination of compound of formula (II) with chlorinating agent in absence of an organic solvent followed by concentration of the reaction mixture, adjusting to neutral pH and isolating bendamustine hydrochloride free from N-alkylated impurities after treating with hydrochloric acid.

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中国工程科技知识中心

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