A method and system for generating an enhanced image of a volume of tissue, the method comprising: emitting acoustic waveforms toward the volume of tissue； detecting a set of acoustic signals derived from acoustic waveforms interacting with the volume of tissue； generating, from the set of acoustic signals, an initial model representing a distribution of an acoustomechanical parameter across a region of the volume of tissue； extracting a set of frequency components, from the set of acoustic signals； generating a first simulated wavefield with a first frequency component of the set of frequency components； generating an updated model of the initial model with the first simulated wavefield； iteratively refining the updated model with a set of simulated wavefields associated with the set of frequency components until a threshold condition is satisfied, thereby producing a final model； and generating the enhanced image from the final model of the volume of tissue.
