ZymoGenetics; Inc.;Ares Trading S.A.;ZymoGenetics, Inc.
发明人:
Busby, Sharon J.,Papasouliotis, Orestis,Nestorov, Ivan,Gross, Jane A.,Munafo, Alain,Pena Rossi, Claudia,Visich, Jennifer
申请号：
AU2008265974
公开号：
AU2008265974B2
申请日:
2008.06.13
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
In various embodiments, the present invention provides methods, compositions,dosing, and administration schedules for treatment of autoimmune diseases,including systemic erythematosus (SLE), for example, comprising administeringto a patient in need of such treatment a TACI-Ig fusion molecule such as atacicept.In one embodiment, the TACI-Ig fusion molecule is administered in amount sufficientto slow, suppress or inhibit proliferation-inducing functions of BLyS and APRIL,in particular the use of multiple administrations of the fusion molecule at relativelylow dose over the course of the treatment.
