Institute of Disease Prevention and Control; Academy of Militaary Medical Sciences
发明人:
Huanle LUO,Guohui Chang
申请号：
US15761760
公开号：
US20200237901A1
申请日:
2016.11.25
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention discloses a bioactive preparation specific against variola virus infection model strains and applications thereof. The application provided by the present invention specifically is the use of bioactive preparation CH2009 in following (1) or (2): (1) preparing the products for inhibiting poxvirus infection； or (2) using for inhibiting poxvirus infection. Bioactive preparation CH2009 is a bioactive preparation specific against poxvirus infection prepared and obtained from inflammatory skin tissues by intradermal vaccination of New Zealand white rabbit with vaccinia virus, and through the steps such as high temperature and pressure, solvent extraction, acid-base treatment, adsorption, elution, concentration by centrifugation and others. The present invention provides a completely new design strategy for the development of new generation of drugs against poxviridae infection such as smallpox and others, and it is no doubt that the resultant antiviral drugs have a wide application prospect and a huge commercial value.
