Morimoto, Alyssa M.,McBride, Jacqueline,Boismenu, Richard,Drappa, Jorn,Maciuca, Romeo,Kennedy, William D.,Townsend, Michael J.
申请号：
AU2012249601
公开号：
AU2012249601A1
申请日:
2012.04.26
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The invention provides methods and compositions for treating various autoimmune diseases (such as systemic lupus erythematousu) with an interferon inhibitor ( such as an anti-intereron-alpha monoclonal antibody). More specifically, the invention provides a method of diagnosing, monitoring and adjusting the treatment of such a patient by way of an interferon signature metric (interferon response gene measurement value), a certain anti-dsDNA antibody titre or being ENA-(leverls of extractable nuclear antigens lower than a healthy level). Furthermore, the invention provides articles of manufacture associated with such a diagnosis.
