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Binding molecules for BCMA and CD3
专利权人:
Boehringer Ingelheim International GmbH
发明人:
Kufer, Peter,Raum, Tobias,Hoffmann, Patrick,Kischel, Roman,Lutterbuese, Ralf,Rau, Doris,Adam, Paul,Borges, Eric,Hebeis, Barbara,Hipp, Susanne
申请号:
AU2012327200
公开号:
AU2012327200A8
申请日:
2012.11.15
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2012327200A820160218.pdf#####Abstract The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule. 199
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