Surgical device (1) including: - a set of handles (30) comprising a housing (10) forming a housing, an element of the stationary handle (11), and an element of the mobile handle (13) which can be displaced by means of an actuating movement, at least one loading unit (40) is able to be mounted at least partially of a reversible manner inside said housing (10) forming a housing, said device (1) being characterized in that said housing (10) forming a housing supports: - a first actuating shaft (16a) mounted in a longitudinal movement inside the housing in reaction to a movement of the mobile handle (13) - a transmission element (17) mounted so as to actuate a longitudinal movement of a second actuating shaft (16b) mounted inside said housing forming a housing (10), in reaction to the longitudinal movement of the first actuating shaft (16a) - a sled with main actuator (20a) and actuating a sled with a secondary (20b) mounted so as to receive at least partially, said at least one loading unit disposable (40), said actuating sledges (20a, 20b) being fixed respectively to the shafts of actuation (16b, 16a) for activating the mechanism for actuating the loading unit (40) in disposable reaction to their longitudinal movements.Dispositif chirurgical (1) comprenant : - un ensemble de poignées (30) comprenant un boîtier (10) formant logement, un élément de poignée stationnaire (11), et un élément de poignée mobile (13) pouvant être déplacé au moyen dun mouvement dactionnement au moins une unité de chargement jetable (40) apte à être montée au moins partiellement de manière réversible à lintérieur dudit boîtier (10) formant logement ledit dispositif (1) étant caractérisé en ce que ledit boitier (10) formant logement supporte : - un premier arbre dactionnement (16a) monté pour un mouvement longitudinal à lintérieur du logement en réaction à un mouvement de lélément de poignée mobile (13) - un élément de transmission (17) monté pour actionner un mouvement longitudinal dun secon