CHILDREN'S HOSPITAL MEDICAL CENTER;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HE
发明人:
Daniel T. STARCZYNOWSKI,Craig J. THOMAS,Garrett RHYASEN,Katelyn MELGAR,Morgan MacKenzie WALKER,Jian-kang JIANG
申请号：
US16804518
公开号：
US20200199123A1
申请日:
2020.02.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as head and neck squamous cell carcinoma (HNSCC), cancer, blood disorders, etc.). Additional embodiments provide synergistic combinations of a BCL2 inhibitor with an IRAK inhibiting compound, and methods of using same.
