The present invention proposes an ultrasound imaging system and method for measuring a property of a region of interest in a subject by using shear wave, wherein an ultrasound probe is configured to sequentially transmit, to each of a plurality of focal spots (320, 322, 324) in the region of interest, a push pulse (310, 312, 314) for generating a shear wave (330, 332, 334), each of the plurality of focal spots having a mutually different depth value (z1, z2, z3), and to receive ultrasound echo signals adjacent (350, 352, 354) to each of the plurality of focal spots a shear wave detector is configured to derive, for each of the plurality of focal spots, a first parameter indicating a property of the generated shear wave, based on the received ultrasound echo signals and a property estimator is configured to estimate a second parameter indicating the property of the region of interest 342 as a function of the derived first parameters.