SELS DE L'ESTER DU (1R*,2R*,4R*)-2-(2-{[3-(4,7-DIMETHOXY-1H-BENZOIMIDAZOL-2-YL)-PROPYL]-METHYL-AMINO}-ETHYL)-5-PHENYL-BICYCLO[2.2.2]OCT-5-EN-2-YLE DE L'ACIDE ISOBUTYRIQUE
ABELE, STEFAN,COMBES, STEPHANIE,FUNEL, JACQUES-ALEXIS,HILPERT, KURT,HUBLER, FRANCIS,REICHENBAECHER, KATHARINA,RENNEBERG, DORTE,VON RAUMER, MARKUS
申请号:
CA2740722
公开号:
CA2740722C
申请日:
2009.10.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to crystalline salts of isobutyric acid(1R*,2R*,4R*)-2-(2-{[3-(4,7-dimethoxy-1H-benzoimi-dazol-2-yl)-propyl]-methyl-amino}-ethyl)-5-phenyl-bicyclo[2.2.2]oct-5-en-2-ylester, processes for the preparation thereof, phar-maceuticalcompositions containing said crystalline salts, and their use as medicaments,especially as calcium channel blockers.