An agricultural sprayer (100) is disclosed. The agricultural sprayer (100) comprises a sprayer system (200) having a chassis supporting a solution tank (210) and a boom assembly (270) mounting spray nozzles (274-285), the sprayer system (200) comprising: a solution circuit including solution lines (244, 250, 366, 368) and a solution pump (242) coupled to the solution tank (210) to pump a solution from the solution tank (210) through the solution lines (244, 250, 366, 368) to the spray nozzles (274-285) an air circuit (400) including air lines (412, 414) and a source of compressed air (410) to selectively introduce air pressure into the solution circuit and a control system including a controller (450) operatively coupled to at least one control valve (226, 230, 246, 306, 320, 350, 360, 369, 370, 390, 420, 422, 430) configured to control flow of the solution and the compressed air through the solution lines (244, 250, 366, 368) wherein the controller (450) is configured to perform a spray cycle in which, during a primary portion of the spray cycle, the at least one control valve (226, 230, 246, 306, 320, 350, 360, 369, 370, 390, 420, 422, 430) is controlled to isolate the air circuit (400) from the solution circuit so that the solution is pumped by the solution pump (242) from the solution tank (210) to the spray nozzles (274-285), and in which, during an air pressure application portion of the spray cycle, the at least one control valve (226, 230, 246, 306, 320, 350, 360, 369, 370, 390, 420, 422, 430) is controlled so that the solution in the solution lines (244, 250, 366, 368) is forced through at least a portion of the solution circuit by the compressed air from the air source (410). Furthermore a method for operating an agricultural sprayer (100) is disclosed.