COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND TIGIT INHIBITORS

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专利权人:

发明人:

申请号：

EP15801009.0

公开号：

EP3215536A1

申请日:

2015.10.29

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention describes combination therapy comprising an OX40 binding agonist and an agent that decreases or inhibits TIGIT expression and/or TIGIT activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired, such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.

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