Rice, Scott A.,Barraud, Nicolas,Kjelleberg, Staffan,Webb, Jeremy S.
申请号:
AU2006251861
公开号:
AU2006251861B2
申请日:
2006.05.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to methods for promoting dispersal of, or preventing formationof microbial biofilms, comprising: exposing a biofilm to an effective amountof nitric oxide or at least one nitric oxide generating or releasing agent; treatinga surface or medium susceptible to biofilm formation with an effective amountof nitric oxide or at least one nitric oxide generating or releasing agent; incorporatingan effective amount of nitric oxide or at least one nitric oxide generating orreleasing agent in a surface or medium susceptible to biofilm formation; or inducingthe accumulation of one or more reactive oxygen or nitrogen species within microorganismswithin said biofilm or capable of forming a biofilm. The invention also relatesto methods for maintaining or enhancing or maintaining and enhancing the functioningof a biofilm, comprising exposing a biofilm to at least one nitric oxide scavenger,at least one antioxidant or at least one nitric oxide scavenger and at least oneantioxidant. The invention also relates to compositions for promoting dispersalof, or preventing formation of microbial biofilms, or for maintaining or enhancingor maintaining and enhancing the functioning of microbial biofilms.