#$%^&*AU2012200157A120120209.pdf#####C\NRPonbIhDCOREC\4075614_ .DOC-1/1012012 ABSTRACT The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating Bcr-Abl, FLT-3, EGFR, c-Kit, B-raf, and NPM-ALK associated cancers, in a subject in need thereof.