Agent for reducing the useable calorie content of food and for therapeutic reduction of weight, in particular for use in the case of adiposity (obesity)
#$%^&*AU2013211517B220160630.pdf#####63 ABSTRACT Agent for reducing the useable calorie content of food and for therapeutic reduction of weight, in particular for use in the case of adiposity (obesity) The invention provides a pharmaceutical composition comprising 5-D-fructose dehy5 drogenase in combination with one or more enzyme(s) selected from glucose isomerase, invertase, lactase, maltase, alpha-amylase, beta-amylase, glucoamylase, pullulanase, isoamylase, amyloglucosidase and cyclomaltodextrin glucanotransferase; but excluding pharmaceutical compositions in which the sole said enzymes present are a combination of 5-D-fructose dehydrogenase and glucose isomerase. 10 Also provided are the use of 5-D-fructose dehydrogenase in treating or preventing adiposity and the treatment of foodstuffs with 5-D-fructose dehydrogenase in order to reduce the calorie content or effective fructose content of the foodstuff. 15