An ultrasound scalpel that may be used for surgical operations is disclosed in this invention. The ultrasound scalpel comprises an ultrasound generator, housing, transducer horn, retaining member and scalpel blade. The device is able to utilize sharp stainless steel surgical blades amenable to being produced as disposable single-use replacement blades. Ultrasonic energy transmitted from transducer horn to surgical blade causes bending waves to be created due to the off-center attachment and/or placement of the surgical blade. This device may be utilized for cutting through skin and/other soft tissues during surgical operations, thereby enhancing cutting efficacy, decreasing and/or eliminating necrosis formation.
