An apparatus for use with an imaging device for imaging a portion of a patient during exertion by the patient. The apparatus may include a first anchor for opposing a force applied by the patient to the first anchor in response to flexing one or more muscles in the imaged portion of the patient. There may also be provided second anchors that assist in restricting motion of the patient in response to the force applied to the first anchor. A plurality of fiducial markings may be provided that are evident in the obtained image to define a reference in the image for determining a location of a region of interest within the portion of the patient relative to the fiducial markings. The region of interest may correspond to an indication of a condition or disease (e.g., exertional compartment syndrome).
