BAKER HEART AND DIABETES INSTITUTE;MONASH UNIVERSITY;MONASH UNIVERSITY;莫拿什大學
发明人:
R‧H‧里奇,秦承雪,A‧克里斯托珀勒斯,P‧M‧塞克斯通,J‧B‧貝爾
申请号：
HK18106820.3
公开号：
HK1247119A
申请日:
2018.05.25
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
The present invention relates generally to a method of therapeutically or prophylactically treating ischaemia-induced myocardial tissue damage, in particular ischaemia-reperfusion-induced myocardial tissue damage. More particularly, the present invention relates to a method of reducing the extent of ischaemia-induced myocardial tissue damage in a mammal by selectively upregulating FPR1-mediated ERK signalling. The method of the present invention is useful, inter alia, in reducing the extent and/or severity of myocardial tissue damage associated with conditions characterized by myocardial ischaemia or myocardial ischaemia and reperfusion, such as acute myocardial infarction caused by atherosclerotic artery occlusion or blood clot-induced artery occlusion.
