A method for the prevention of atopic illness in infants born to mothers with IgE-dependent disease involves use of anamnestic data for the selection of newborns to atopic illness risk group, use of breast feeding in combination with nursing woman balanced diet containing all required nutrients, or prescription of partially or extensively hydrolyzed infant formulas if breast nursing is impossible, elimination of pernicious habits in mother and limitation of pollutants in house. Levels of general Ig are determined in mother and infant. If level of general Ig in mother is more than 197±28.11 IO/ml or in infant is more than 13.65±3.52 IO/ml, in addition specific Ig to panels of food, domestic and pollen (mixt-allergens) allergens typical for given region are determined. If level of specific IgE in mother is more than 0.68 ±0.11 Cu/ml, in infant is more than 0.1 Cu/ml in case of domestic allergens measures for elimination of dust and epidermal allergens of domestic animals and birds are prescribed. In case of pollen allergens recommended is the exclusion of herbs from food regimen of mother and infant, cross-reaction products, medicinal agents containing herbs, flowering plants from infant house. In case of food allergens causally weighty food allergens, preservation agents, synthetic food colorants, taste boosters are eliminated from regimen of nursing woman and infant. If breast nursing is impossible partially or extensively hydrolyzed infant formulas and NC-3PUFA are used.Способ профилактики атопического заболевания у грудных детей, родившихся от матерей с IgE-зависимым заболеванием, путем использования анамнестических данных для отбора новорожденных в группу риска атопического заболевания, использование грудного вскармливания в сочетании со сбалансированной диетой женщины-кормилицы, которая содержит все необходимые нутриенты, при невозможности грудного вскармливания - назначение смесей с частично или полностью гидролизированной формулой, исключение вредных привычек