組蛋白去乙醯基酶之抑制劑农业专利-农业专业知识服务系统

发明人:: TESSIER, PIERRE,皮尔泰瑟,皮爾泰瑟,LEIT, SILVANA,希尔维纳莱特,希爾維納萊特,SMIL, DAVID,大卫斯密尔,大衛斯密爾,DEZIEL, ROBERT,罗伯特丹兹尔,羅伯特丹茲爾,AJAMIAN, ALAIN,艾伦亚杰曼,艾倫亞傑曼,CHANTIGNY, YVES ANDRE,艾维斯安得烈钱丁尼,艾維斯安得烈錢丁尼,DOMINGUEZ,

摘要：: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula compounds of the Formula (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein groups L, M, X and Y are as defined herein.本發明係關於抑制組蛋白去乙醯酶之化合物。更特定言之,本發明係提供式(I)化合物及其N-氧化物、水合物、溶劑合物、藥學上可接受之鹽、前體藥物及複合物,及其外消旋與呈比例混合物、非對映異構物及對掌異構物,其中基團L,M,X及Y均如本文定義。