The present invention relates to granular functionalized silicas, wherein the Hg pore volume (<；4 &mu；m) is more than 0.80 ml/g, dQ3=10% is more than 400 &mu；m, dQ3=90% is less than 3000 &mu；m, the ratio of d50 without ultrasound exposure to d50 after 3 min of ultrasound exposure is <；4.00 and the carbon content is 1.0-15.0% by weight. The inventive granular functionalized silicas can be used as a support material, especially as a support for enzymes.
