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Treatment of heart failure in non-human mammalian animals with an aldosterone antagonist
专利权人:
CEVA SANTE ANIMALE
发明人:
Ovaert, Patricia,Bernay, Florence,Guyonnet, Jérôme
申请号:
ES12180375
公开号:
ES2566923T3
申请日:
2008.06.25
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Veterinary composition for use in the treatment of heart failure in dogs and / or cats comprising spironolactone or its metabolites chosen from canrenone, canrenoic acid, 15 (3-OH canrenone, 21-OH canrenone, potassium canrenoate, 7α-thio -spironolactone, 7α-thiomethylpyronolactone and 6 (β-hydroxy-7-α-thiomethylpyronolactone, and a pharmaceutically acceptable vehicle, characterized in that said spironolactone or its metabolites are administered at a therapeutic dose between 2 and 5 mg / kg / day, in a single take, in association with an inotrope.Composicion veterinaria para su utilization en el tratamiento de la insuficiencia cardiaca en perros y/o gatos que comprende espironolactona o sus metabolitos elegidos entre canrenona, acido canrenoico, 15(3-OH canrenona, 21- OH canrenona, canrenoato de potasio, 7α-tio-espironolactona, 7α-tiometilespironolactona y 6(β-hidroxi-7-α- tiometilespironolactona, y un vehiculo farmaceuticamente aceptable, caracterizada por que dicha espironolactona o sus metabolitos se administran a una dosis terapeutica comprendida entre 2 y 5 mg/kg/dia, en una sola toma, en asociacion con un inotropo.
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