THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
发明人:
CHEN, WEN-TIEN
申请号：
CA2422162
公开号：
CA2422162C
申请日:
2001.08.28
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to novel methods and compositions for detectionand isolation of cancer cells with metastatic potential. The invention furtherrelates to assays for measuring the metastatic potential of such cancer cellsand drug screening assays for the identification of agents having anti-metastatic potential. The present invention further provides methods andcompositions for inhibiting the metastatic potential of cancer cells bymodulating the activity of serine integral membrane proteases [(SIMP)consisting of seprase and dipedidyl peptidase IV (DPPIV) ]expressed on thesurface of metastasizing cancer cells.
