The present invention relates to spirocyclic amide derivatives of the formula I,pharmaceutically acceptable salts thereof, a process for their preparation, pharmaceutical compositions containing them, and their use in therapy.本發明有關式I之螺環狀醯胺衍生物其醫藥上可接受之鹽、其製備方法、含其之醫藥組合物,及其於治療之用途。