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IAP BIR domain binding compounds
专利权人:
Pharmascience Inc.
发明人:
Jaquith, James,Jarvis, Scott,Boudreault, Alain,Laurent, Alain,Bureau, Patrick
申请号:
AU2007250443
公开号:
AU2007250443B2
申请日:
2007.05.16
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention discloses an isomer, enantiomer, diastereoisomer, tautomer,prodrug, pharmaceutically acceptable salt of a compound of formula I and pharmaceuticalcompositions thereof useful in modulating IAP function via preventing bindingof a BIR binding protein to an IAP BIR domain and in treating proliferative diseasessuch as cancer Also, disclosed is a compound of formula I labeled with a detectablelabel or affinity tag useful as a probe in identifying compounds that bind to anIAP BIR domain.
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http://www.ckcest.cn/home/
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