Methods and systems for planning a bronchoscopic lung volume reduction procedure, such as placement of a one-way valve or biosealant or energy delivery in a patients lungs. The system may include a processor and programming operable on the processor for planning the lung volume reduction procedure. Planning the lung volume reduction procedure by the processor may include receiving patient volumetric images, analyzing the images to identify the lobes and airway tree of the lungs, displaying a three dimensional model of the lungs, generating and displaying a suggested treatment volume on the three dimensional model, receiving a selected treatment volume from a user, generating and displaying a suggested treatment location within the airway tree, receiving a selected treatment location within the airway tree from the user, receiving a selected treatment modality from the user, and displaying a treatment plan.