The present technology relates to an information processing device, an information processing system, and a program which enable a state of pores to be understood in further detail.A photographing unit photographs skin of a person irradiated with first light of a first wavelength band or second light of a second wavelength band different from the first wavelength band. A pore detecting unit detects pores in a first skin image, which is an image obtained by photographing the skin of the person irradiated with the first light. A porphyrin detecting unit detects a pore state of the skin of the person based on pixel values of a plurality of color components of each of pixels of a second skin image, which is an image obtained by photographing the skin of the person irradiated with second light. A display control unit distinguishes pores in which an abnormality is detected and normal pores based on a detection result of the pores and the pore state of the skin of the person and control display of the pore state of the skin of the person. The present technology can be applied to a system for analyzing a pore state of skin, for example.