PROBLEM TO BE SOLVED: To provide methods of treating psoriasis using IL-17 receptor antagonists.SOLUTION: A method of treating psoriasis comprises the steps of: a) administering an IL-17 binding molecule to a patient in need thereof during an induction regimen, wherein the induction regimen comprises a loading regimen, and the loading regimen comprises administering the patient five doses of about 150 to about 300 mg of the IL-17 binding molecule, each of the five doses being delivered weekly, beginning on week zero and b) thereafter administering the IL-17 binding molecule to the patient during a maintenance regimen.COPYRIGHT: (C)2014,JPO&INPIT【課題】IL-17受容体抗体を用いる乾癬治療法の提供。【解決手段】a)導入レジメン中にIL-17結合性分子をそれを必要とする患者に投与するステップであり、ここで導入レジメンは、負荷レジメンを含み、負荷レジメンは、ゼロ週目に始めて、IL-17結合分子を約150mg~約300mgの用量で5回患者に投与することを含み、5回の用量のそれぞれは週1回送達する、前記ステップと、b)その後、維持レジメン中にIL-17結合性分子を患者に投与するステップとを含む。【選択図】なし
