The disclosure relates generally to therapeutic nanoparticles. Exemplary nanoparticle disclosed herein may include about 0.The diblock poly- (lactic acid) of the therapeutic agent of 1 to about 40 weight % and about 10 to about 90 weight %, poly- (ethylene-ethylene glycol copolymer) or diblock) poly- (lactic acid -co- poly(ethylene glycol)-poly- (ethylene) diol copolymer, wherein poly- (lactic acid-ethylene glycol copolymer) (ethylene) of diblock includes that poly- (lactic acid) acid has number equal molecular wt about 30- about 90- or diblock) poly- (lactic acid -co- poly(ethylene glycol)-poly- (ethylene) glycol copolymer) include that poly- (lactic acid -co- poly(ethylene glycol) acid has the protein of several equal molecular wt about 30- about 90.
