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SIALIC ACID TO SUPPORT SALIVATION
专利权人:
НЕСТЕК С.А. (CH)
发明人:
ШПРЕНГЕР Норберт (CH),ВИДАЛЬ Карин (CH),ШЕРБЮ Кристин (CH),ЯНН Альфред (FR)
申请号:
RU2010150148/15
公开号:
RU2010150148A
申请日:
2009.05.06
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A composition containing sialic acid for the treatment and / or prevention of diseases associated with impaired salivation. ! 2. The composition according to claim 1, in which sialic acid is N-acetylneuraminic acid. ! 3. The composition according to claim 1, in which sialic acid is associated with a peptide / protein framework enriched in threonine. ! 4. The composition according to claim 1, containing a protein fraction, where the protein fraction contains from about 7 to 25 wt.% Sialic acid and threonine in an amount of from about 8 to 22% of the total number of amino acids. ! 5. The composition according to claim 1, in which sialic acid is provided as an oligosaccharide ingredient containing glycocosylated amino acids and peptides of the general formula, RnSacm, where R is an amino acid residue, Sac is a monosaccharide selected from the group consisting of N-acetylneuraminic acid, N-acetylgalactosamine and galactose, n has a value between 1 and 10 with the proviso that if n is 1, then R is a threonine or serine residue, and if n has a value between 2 and 10, then the peptide contains at least one residue tr eonine or serine, m has a value of from 2 to 4 and at least 15 mol% of the ingredient is N-acetylneuraminic acid. ! 6. The composition according to claim 1, in which the disease associated with impaired salivation is selected from the group consisting of dysphagia, xerostomia, and combinations thereof. ! 7. The composition according to claim 1, where the composition is a pharmaceutical composition, food product, food supplement or nutraceutical. ! 8. The composition according to claim 1, where the composition further comprises a neuroprotective agent, such as antioxidant plant extracts, vitamin1. Композиция, содержащая сиаловую кислоту для лечения и/или профилактики заболеваний, связанных с нарушенным слюноотделением. ! 2. Композиция по п.1, в которой сиаловая кислота является N-ацетилнейраминовой кислотой. !3. Композиция по п.1, в которой сиаловая кислота
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