LIU WEIGUO,DING FA XIANG,SUN WANYING,DEJESUS REYNALDA KEH,TANG HAIFENG,HUANG XIANHAI,JIAN JINLONG,GUO YAN,WANG HONGWU
申请号:
IN201847031203
公开号:
IN201847031203A
申请日:
2018.08.20
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention relates to bicyclic aryl monobactam compounds of Formula (I) and pharmaceutically acceptable salts thereof wherein A1 L M W X Y Z RX and Rz are as defined herein. The present invention also relates to compositions which comprise a bicyclic aryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention either alone or in combination with a therapeutically effective amount of one or more beta-lactamase inhibitor compounds.