The purpose of the present invention is to provide a freeze dried preparation having improved hepatocyte growth factor storage stability in comparison to conventional freeze dried preparations. The present invention provides a freeze dried preparation containing (1) hepatocyte growth factor (2) trehalose and (3) one or more compounds selected from the group consisting of arginine histidine lysine meglumine glutamic acid aspartic acid proline creatine creatinine trishydroxymethylaminomethane and pharmacologically acceptable salts of these.