James John Crawford,Daniel Fred Ortwine,BinQing Wei,Wendy B. Young
申请号：
US13667133
公开号：
US20130116235A1
申请日:
2012.11.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X1, X2, and X3 are N, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
