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METHOD FOR DIFFERENTIAL DIAGNOSIS OF OPTIC NERVE HEAD DRUSEN AND CONGESTIVE OPTIC DISCS BY OPTICAL COHERENT TOMOGRAPHY-ANGIOGRAPHY
专利权人:
Federalnoe gosudarstvennoe avtonomnoe uchrezhdenie "Natsionalnyj meditsinskij issledovatelskij tsentr "Mezhotraslevoj nauchno-tekhnicheskij kompleks "Mikrokhirurgiya glaza" imeni akademika S.N. Fedoro
发明人:
Kabanova Evgeniya Anatolevna (RU),Кабанова Евгения Анатольевна (RU),Iojleva Elena Eduardovna (RU),Иойлева Елена Эдуардовна (RU),Zinoveva Aleksandra Vitalevna (RU),Зиновьева Александра Витальевна (RU)
申请号:
RU2019126914
公开号:
RU0002718322C1
申请日:
2019.08.27
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to ophthalmology, and can be used for differential diagnostics of optic nerve head (ONH) drusen and congestive optic nerve (ON) discs. Perfusion density is measured in three topographic zones of ONH: central (Central), internal (Inner) and temporal quadrant of external zone (Outer temporalis) by method of optical coherent tomography of angiography by protocol Angiography Analysis: Angiography 6X6 mm. Based on the obtained data, the ONH perfusion coefficient is calculated by formula: ONH perfusion coefficient = (Perfusion Density Inner – Perfusion Density Central) / Perfusion Density Inner × 100. If the ONH perfusion coefficient is 16.3 to 22.3, the perfusion density of the central area is 0.398 to 0.428, the density of perfusion of the temporal quadrant of the external area is 0.435 to 0.455, ONH drusen are diagnosed. If the ONH perfusion coefficient is 29.5 to 34.5, the central perfusion density is 0.332–0.360, the density of perfusion of the temporal quadrant of the external area is 0.404 to 0.434, the stagnant ON discs are diagnosed.EFFECT: method provides differential diagnosis of ONH drusen and congestive ON discs by evaluating perfusion density in the ONH region.1 cl, 2 exИзобретение относится к медицине, а именно к офтальмологии, и может быть использовано для дифференциальной диагностики друз диска зрительного нерва (ДЗН) и застойных дисков зрительного нерва (ЗН). Измеряют плотность перфузии (Perfusion Density) в трех топографических зонах ДЗН: центральной (Central), внутренней (Inner) и височном квадранте наружной зоны (Outer temporalis) методом оптической когерентной томографии ангиографии по протоколу Angiography Analysis: Angiography 6X6 mm. На основании полученных данных рассчитывают коэффициент перфузии ДЗН по формуле: коэффициент перфузии ДЗН = (Perfusion Density Inner - Perfusion Density Central)/ Perfusion Density Inner × 100. Если коэффициент перфузии ДЗН от 16,3 до 22,3, плотность перф
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