Mark J. Graham; III;Thomas A. Bell, III;Rosanne M. Crooke;Thomas A. Bell
发明人:
Thomas A. Bell, III,Rosanne M. Crooke,Mark J. Graham
申请号：
US13639837
公开号：
US20130053430A1
申请日:
2011.04.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided herein are methods, compounds, and compositions for reducing expression of a CETP mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for increasing HDL levels and/or HDL activity and reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.
